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Received β€” 9 October 2025 ⏭ Epigenetics

FBLN2 promoter hypermethylation: a negative prognostic biomarker and anti-PD-1 response predictor in clear cell renal cell carcinoma via high-throughput CpG Island screening

βœ‡Most Recent Articles: Clinical Epigenetics
By: Wenfeng Liao Β· Lianzi Yu Β· Lufang Zhang Β· Jie Shao Β· Guanhua Li Β· Jialei Hua Β· Shuya Zhao Β· Li Jia Β· Yawei Han Β· Aimin Zhang Β· Xin Yao Β· Yueguo Li and Dong Dong
8 October 2025 at 08:00
Clear cell renal cell carcinoma (ccRCC), with rising incidence globally, shows heterogeneous responses to immune checkpoint blockade (ICB). DNA methylation dysregulation impacts tumor immunity, necessitating p...

The synergistic action of HDAC inhibitor with cisplatin impedes survival and proliferation of drug-tolerant persister in gastric and liver cancer cells

βœ‡Most Recent Articles: Clinical Epigenetics
By: Anjali Singh Β· Abhiram Natu Β· Flevia Anthony Β· Hemalatha Muthu Β· Bharat Khade Β· Duane T. Smoot Β· Hassan Ashktorab and Sanjay Gupta
8 October 2025 at 08:00
Acquired therapy resistance is a dynamic process associated with early epigenetic modifications reshaping gene transcription across multiple cellular pathways, ultimately giving rise to drug-tolerant persister...

Sex-specific associations between insomnia symptoms and mental health among Chinese young adults and the modified effect of CRY2 gene DNA methylation

βœ‡Most Recent Articles: Clinical Epigenetics
By: Meng Fan Β· Yaqian Niu Β· Wanyu Che Β· Yuming Chen Β· Yuxuan Cao Β· Tangjun Jiang Β· Meng Wang Β· Tingting Li Β· Shuman Tao Β· Yajuan Yang Β· Liwei Zou Β· Fangbiao Tao and Xiaoyan Wu
6 October 2025 at 08:00
The prevalence of insomnia and mental illness varies by sex. The mRNA expression level of the CRY gene in patients with insomnia is significantly decreased, and the expression level of the CRY2 gene is closely re...
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