Nature, Published online: 20 May 2026; doi:10.1038/s41586-026-10564-xl-2-Hydroxyglutarate is identified as a legitimate physiological signalling metabolite, and control of its levels is essential for postnatal growth and survival and correct renal development and function.

Nature, Published online: 01 April 2026; doi:10.1038/s41586-026-10204-4A set of hydroxy promoters physically mixed with cobalt oxides for syngas to light olefins conversion using Fischer–Tropsch synthesis is shown to boost catalyst performance as well as simplifying the process and increasing sustainability.

Cell Death Discovery, Published online: 01 April 2026; doi:10.1038/s41420-026-02969-4Non-enzymatic function of QSOX2 directly regulates the JUNB-ITGB4 axis and enhanced resistance to osimertinib in EGFR-mutation lung adenocarcinoma