Nature, Published online: 08 April 2026; doi:10.1038/s41586-026-10346-5Lesion-targeted immune modulation is a feasible strategy to control cardiac fibrosis, and engineered dendritic cells are a promising therapeutic platform for treating cardiac remodelling and heart failure.

Nature, Published online: 08 April 2026; doi:10.1038/s41586-026-10352-7Engineered Ruddlesden–Popper nickelate superstructures show that specific Fermi surface features enable ambient-pressure superconductivity, linking structural configuration, electronic structure and superconducting behaviour. .

Nature Cancer, Published online: 03 April 2026; doi:10.1038/s43018-026-01141-2Li et al. present PRET, a few-shot system for pan-cancer detection not requiring model fine-tuning, validated it in multicenter datasets and found that it outperformed existing approaches across tasks and pathologists in lymph node metastasis detection.