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A pathogen lncRNA secreted into rice sequesters a host miRNA for virulence

Nature, Published online: 20 May 2026; doi:10.1038/s41586-026-10572-x

A fungal long non-coding RNA from Magnaporthe oryzae translocates into rice cells to sequester a host microRNA that normally represses PKR1, a negative immunity regulator, thereby facilitating infection and revealing a widespread RNA-based pathogen–host interaction mechanism.
  • ✇Nature Cancer
  • A functional map of m<sup>6</sup>A sites in cancer Yalong Wang · Han Xu
    Nature Cancer, Published online: 13 March 2026; doi:10.1038/s43018-026-01137-yRNA N6-methyladenosine (m6A) is the most abundant internal RNA modification, yet its functional landscape in cancer remains poorly defined. A study now introduces a METTL3-based RNA base-editing screen that maps functional m6A sites and reveals m6A-dependent translational activation of the tumor suppressor CHD9 in prostate cancer and beyond.
     

A functional map of m<sup>6</sup>A sites in cancer

13 March 2026 at 08:00

Nature Cancer, Published online: 13 March 2026; doi:10.1038/s43018-026-01137-y

RNA N6-methyladenosine (m6A) is the most abundant internal RNA modification, yet its functional landscape in cancer remains poorly defined. A study now introduces a METTL3-based RNA base-editing screen that maps functional m6A sites and reveals m6A-dependent translational activation of the tumor suppressor CHD9 in prostate cancer and beyond.
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