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Joint impact of pathological burden and cognitive resilience on Alzheimer’s disease risk

Nature Medicine, Published online: 11 September 2026; doi:10.1038/s41591-026-04635-9

A 15-year cohort study shows that Alzheimer’s dementia risk is jointly shaped by Alzheimer’s pathology and cognitive resilience, with high resilience linked to lower risk, even under greater pathology.

Within-family effect of ancestry on complex traits in a Mexican population

Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-11039-9

This study uses a within-family design to identify significant ancestry differences in complex traits such as height and type 2 diabetes in a genetically diverse population from Mexico City.
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