Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-11001-9Temporal protein-abundance measurements from systematically perturbed breast cancer cell lines were generated to develop ProteinTalks, a virtual cell model that functions as an operational tool for diverse drug discovery tasks.

Nature Cancer, Published online: 15 May 2026; doi:10.1038/s43018-026-01169-4Zhao and colleagues show that CD300ld, upregulated in pathologically activated neutrophils, mediates contact-dependent suppression of cytotoxic CD8+ T cells by binding to phosphatidylserine, inhibiting antitumor immune responses.