npj Digital Medicine, Published online: 04 April 2026; doi:10.1038/s41746-026-02573-xHoloTrauma 3X Triadic AI Co reasoning for robot assisted emergency maxillofacial reconstruction

A multi-omic single-cell atlas of the aging mouse brain reveals cell-type-specific transposon methylation changes, strengthening of 3D genome boundaries, and regionally heterogeneous aging signatures. These findings offer a resource to understand the molecular mechanisms of brain aging and guide future research on neurodegeneration.