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Predicting bilingual aphasia treatment outcomes using digital twins: a double-blind randomized controlled trial

npj Digital Medicine, Published online: 10 April 2026; doi:10.1038/s41746-026-02583-9

Predicting bilingual aphasia treatment outcomes using digital twins: a double-blind randomized controlled trial

High-fidelity collisional quantum gates with fermionic atoms

Nature, Published online: 08 April 2026; doi:10.1038/s41586-026-10356-3

A robust composite pair-exchange gate based on controlled interactions of fermionic atoms in an optical superlattice demonstrates high fidelities and long Bell-state lifetimes, marking an important step towards a fully digital fermionic quantum computer.

Deconstruction of a spino-brain–spinal cord circuit that drives chronic pain

Nature, Published online: 01 April 2026; doi:10.1038/s41586-026-10296-y

In mice, a circuit between the spinal cord and various regions of the brain, centring on spinal-cord-projecting neurons in the rostral ventromedial medulla, has a key role in driving chronic pain.

General scales unlock AI evaluation with explanatory and predictive power

Nature, Published online: 01 April 2026; doi:10.1038/s41586-026-10303-2

A fully automated methodology based on rubrics capturing a broad range of cognitive and intellectual demands is illustrated using LLMs and tasks, demonstrating a new way to evaluate the capabilities of AI systems and anticipate their performance.

Reproducibility and robustness of economics and political science research

Nature, Published online: 01 April 2026; doi:10.1038/s41586-026-10251-x

Robustness checks and reproduction of analyses with existing and updated data based on 110 articles in economics and political science journals with data and code-sharing requirements found high levels of robustness and reproducibility and determined that robustness was not dependent on author characteristics or data availability.

Moderate global warming does not rule out extreme global climate outcomes

Nature, Published online: 25 March 2026; doi:10.1038/s41586-026-10237-9

Extreme global climate outcomes may occur even under moderate 2 °C warming and may turn out to be more extreme than model-averaged projections at 3 °C or 4 °C warming.

Human-specific features of the cerebellum and ZP2-regulated synapse development

Human-specific transcriptomic and regulatory features are present in the cerebellum, with ZP2 playing a key role in synapse regulation. ZP2 expression is induced by pontine mossy fibers, leading to decreased synaptic proteins and neuronal activity, which provides insights into the evolutionary development of the human cerebellum.

Author Correction: Global, regional, and national burden of chronic respiratory diseases and impact of the COVID-19 pandemic, 1990–2023: a Global Burden of Disease study

Nature Medicine, Published online: 11 March 2026; doi:10.1038/s41591-026-04288-8

Author Correction: Global, regional, and national burden of chronic respiratory diseases and impact of the COVID-19 pandemic, 1990–2023: a Global Burden of Disease study
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