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A global digital navigator of human health for precision medicine

Nature Medicine, Published online: 11 September 2026; doi:10.1038/s41591-026-04621-1

The International Consortium of Digital Twins in Healthcare and Medicine was established to advance medical digital twin technology as a new infrastructure for precision health.

Skin-innervating glutamatergic neurons modulate aging

Within the skin, glutamatergic neurons expressing neurofilament heavy chain (Nefh) play a role in aging. Loss of Nefh during aging drives skin fibroblast senescence and collagen loss, whereas glutamate supplementation improves skin aging phenotypes.
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