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Received — 10 September 2026 ⏭ Journals

AI-enhanced adaptive virtual screening of large libraries for ligand discovery

✇Nature Biotechnology - Issue - nature.com science feeds
By: Domiziana Cecchini · AkshatKumar Nigam · Ming Tang · Joana Reis · Matt Koop · Andrea Gottinger · Callum Robert Nicoll · Yao Wang · Abhilash Jayaraj · Süleyman Selim Çınaroglu˘ · Ricarda Törner · Yehor Malets · Minko Gehev · Krishna M. Padmanabha Das · Kelly Churion · Jongwan Kim · Nidhin Thomas · Yong Li · Hyuk-Soo Seo · Sirano Dhe-Paganon · Christopher Secker · Mohammad Haddadnia · Alexander Hasson · Minkai Li · Abhishek Kumar · Roni Levin-Konigsberg · Eun-Bee Choi · Geoffrey I. Shapiro · Huel Cox 3rd · Luke Sebastian · Chelsea Braithwaite · Puspalata Bashyal · Dmytro S. Radchenko · Aditya Kumar · Lei Yang · Pierre-Yves Aquilanti · Henry Gabb · Amr Alhossary · Eric O’Neill · Gerhard Wagner · Alán Aspuru-Guzik · Yurii S. Moroz · Charalampos G. Kalodimos · Konstantin Fackeldey · John D. Schuetz · Andrea Mattevi · Haribabu Arthanari · Christoph Gorgulla
1 September 2026 at 08:00

Nature Biotechnology, Published online: 01 September 2026; doi:10.1038/s41587-026-03217-x

Massive chemical libraries are screened computationally at scale.

Targeting peripheral 5-HT2AR enhances antitumor immunity in colorectal cancer

✇Cell
By: YaTing Wen · LingJie Tang · WenWen Duan · QingFei Ren · YangYue Ni · ShiYang Chen · Jun Chen · Lei Yang · Huan Wang · Yuan Chen · YunZhe Zheng · XingChao Pan · Hui Du · MengWen Huang · An Zeng · Zhaocai Zhou · ZhiGang Zhang · HongBin Ji · GaoXiang Ge · Yi Arial Zeng · Wei Zhang · ShiHui Wang · JianJun Cheng · Sheng Wang · JianFeng Chen
4 August 2026 at 08:00
By selectively targeting peripheral 5-HT2AR without inducing psychedelic effects, a non-brain-penetrant agonist boosts antitumor CD8+ T cell immunity and improves immunotherapy responses in preclinical models of colorectal cancer.
Received — 13 April 2026 ⏭ Journals

Asymmetric selection of a rice immune module and rebuild of disease resistance

✇Nature - Issue - nature.com science feeds
By: Hui Lin · Fudan Chen · Guanyun Cheng · Bingxiao Yan · Meng Yuan · Jie Qiu · Yiduo Lu · Mingzhe Suo · Ying Chen · Yijie Wang · Kaixuan Cui · Xiangyu Gong · Shasha Liu · Bofan Liu · Jiyun Liu · Jianjun Wang · Rongbai Li · Bizeng Mao · Jianlong Xu · Jong-Seong Jeon · Xuehui Huang · Bin Han · Dong-Lei Yang · Qifei Gao · Haiming Xu · Yiwen Deng · Gongyou Chen · Zuhua He
8 April 2026 at 08:00

Nature, Published online: 08 April 2026; doi:10.1038/s41586-026-10361-6

Stacking XA48-mediated effector-triggered immunity with XA21-mediated pattern-triggered immunity in Oryza sativa japonica reconstitutes the broad-spectrum resistance from wild rice.
Received — 4 April 2026 ⏭ Journals
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