Nature Cancer, Published online: 11 September 2026; doi:10.1038/s43018-026-01236-wZheng et al. describe how hypoxia-induced methylmalonate semialdehyde dehydrogenase lactylation promotes acyl-CoA synthetase long-chain family member 4 propionylation and degradation, thereby suppressing ferroptosis induced by chemotherapy, and develop a blocking peptide that increased chemotherapy efficacy in pancreatic ductal adenocarcinoma.

Nature, Published online: 07 September 2026; doi:10.1038/s41586-026-11103-4Author Correction: AhR inhibition promotes axon regeneration via a stress–growth switch

Nature, Published online: 01 April 2026; doi:10.1038/s41586-026-10295-zAhR functions as a neuronal brake on axon regeneration, integrating environmental sensing, protein homeostasis and metabolic signalling to control the balance between stress adaptation and axonal repair.