Nature, Published online: 25 March 2026; doi:10.1038/s41586-026-10237-9Extreme global climate outcomes may occur even under moderate 2 °C warming and may turn out to be more extreme than model-averaged projections at 3 °C or 4 °C warming.

Cell Death Discovery, Published online: 24 March 2026; doi:10.1038/s41420-026-03037-7Autophagy inhibition potentiates the antileukemic effect of FLT3 inhibitors and overcomes resistance in FLT3-ITD acute myeloid leukemia

Human-specific transcriptomic and regulatory features are present in the cerebellum, with ZP2 playing a key role in synapse regulation. ZP2 expression is induced by pontine mossy fibers, leading to decreased synaptic proteins and neuronal activity, which provides insights into the evolutionary development of the human cerebellum.