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SPIRIT-CONSORT-ELM: element-level annotated dataset and large language model approach for assessing randomized controlled trial reporting

npj Digital Medicine, Published online: 06 October 2026; doi:10.1038/s41746-026-03318-6

SPIRIT-CONSORT-ELM: element-level annotated dataset and large language model approach for assessing randomized controlled trial reporting

Stroke drives glioma progression through the emergence of tumor-associated astrocytes with reduced Ca<sup>2+</sup> activity

Nature Cancer, Published online: 25 September 2026; doi:10.1038/s43018-026-01238-8

Lee and colleagues report that ischemic stroke induces the generation of an astrocytic population that, through reduced calcium signaling, favors the recruitment of tumor-associated macrophages, thereby promoting glioma invasion in preclinical models.

An iron-regulated methionine redox axis governs adipose browning and cancer cachexia

Nature Cancer, Published online: 22 September 2026; doi:10.1038/s43018-026-01234-y

Chio and colleagues describe an iron-dependent pathway with a role in the induction of cancer cachexia-linked events such as adipose browning and identify methionine sulfoxide reductase A as an important and targetable factor in this process.
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