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Received — 10 September 2026 ⏭ Nanotechnology

Molecular Therapy Advances
Development of the “EASY-HSV system” based on HSV-1 genome-maintaining 293 cells Fumio Maeda · Moeka Nobe · Kenichiro Imai · Shungo Adachi · Tohru Natsume
Maeda and colleagues established of a 293-based cell line stably maintaining the HSV genome. This cell line enables efficiently producing HSV amplicon vectors without purification or transfection of the HSV genome. This system offers a more practical platform for HSV-based gene delivery, overcoming several limitations associated with conventional methods.
31 August 2026 at 08:00

Development of the “EASY-HSV system” based on HSV-1 genome-maintaining 293 cells

By: Fumio Maeda · Moeka Nobe · Kenichiro Imai · Shungo Adachi · Tohru Natsume

31 August 2026 at 08:00

Maeda and colleagues established of a 293-based cell line stably maintaining the HSV genome. This cell line enables efficiently producing HSV amplicon vectors without purification or transfection of the HSV genome. This system offers a more practical platform for HSV-based gene delivery, overcoming several limitations associated with conventional methods.