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Received — 18 September 2026 ⏭ Cell

Cell
Dietary arginine drives codon-dependent MHC class I translation and improves immunity in colon tumorigenesis and respiratory viral infection Qiushuang Wu · Lara M. Seydlitz · Vladislav Iakimov · Dennis J. Hsu · Parham Habibzadeh · H. Heinrich Hoffmann · Philip B. Paty · Charles M. Rice · Sohail F. Tavazoie
Arginine availability regulates arginyl tRNA levels and codon-dependent translation of MHC class I, tuning antigen presentation and shaping anti-viral and anti-tumor immunity.
30 July 2026 at 08:00

Dietary arginine drives codon-dependent MHC class I translation and improves immunity in colon tumorigenesis and respiratory viral infection

Cell

By: Qiushuang Wu · Lara M. Seydlitz · Vladislav Iakimov · Dennis J. Hsu · Parham Habibzadeh · H. Heinrich Hoffmann · Philip B. Paty · Charles M. Rice · Sohail F. Tavazoie

30 July 2026 at 08:00

Arginine availability regulates arginyl tRNA levels and codon-dependent translation of MHC class I, tuning antigen presentation and shaping anti-viral and anti-tumor immunity.