Login
Localized PD-1 CAR T therapy reprograms neuroinflammation
21 July 2026 at 08:00
PD-1+ T follicular helper-like cells drive B cell-associated pathology in multiple sclerosis. Programmable PD-1-targeting CAR T cells selectively eliminate these pathogenic CD4 T cells while delivering IL-10 at sites of inflammation, thereby suppressing neuroinflammation across preclinical models.
