An experimental compound called AP503 significantly strengthened bones in mice by activating GPR133, a receptor that boosts bone formation while slowing bone loss. Because the same treatment has also been linked to stronger muscles, researchers see intriguing potential for combating age-related decline and osteoporosis.

Semaglutide, the drug found in Ozempic and Wegovy, was linked to nearly 40% fewer asthma attacks in a large real-world study. It was also associated with about 20% fewer COPD flare-ups. Researchers say GLP-1 drugs may offer respiratory benefits in addition to their effects on diabetes and obesity, but clinical trials are needed to confirm the findings.

Two major alien-life announcements in 2025 generated enormous excitement, but most astrobiologists remained unconvinced. Only 6.6% of surveyed experts thought possible biological molecules on K2-18b probably represented extraterrestrial life, while 15.1% said the same about intriguing mineral patterns in a Martian rock.

Interstellar comet 3I/ATLAS contains exceptionally high levels of methanol, suggesting it formed under conditions very different from those that shaped most comets in our solar system. ALMA also revealed that tiny icy grains around the comet are releasing methanol like miniature comets, giving astronomers an unusually detailed look at an object from another star system.

Britain’s towering Devil’s Arrows were built from 25-tonne stones hauled at least 18 kilometers from Brimham Rocks around 4,000 years ago. The discovery reveals an astonishing feat of prehistoric engineering and suggests the stones’ distant source may have been chosen for cultural or spiritual reasons.

Insects quietly hold much of the natural world together, yet conservation efforts are overlooking the tropical regions where more than 80 percent of insect species live. Monash University researchers have developed a global framework to close this gap by combining scientific studies with museum collections, local expertise, citizen science, social media records, and new technologies.

Scientists found that a tiny atomic structure that forms on nickel oxide during methane conversion is more effective than the metallic nickel long believed to drive the reaction. The discovery allowed a low-nickel catalyst to rival one containing 10 times more metal, potentially opening the door to cheaper and more efficient industrial catalysts.

Volcanic rocks in Colombia are rewriting the timeline of the collision between Central and South America. Their magnetic signatures show that major tectonic deformation had already weakened by the late Miocene, suggesting the most intense collision occurred earlier than previously believed.

A new analysis of more than 1,700 supernovae is questioning whether the universe is really accelerating at all. After accounting for the ages of the stars that produce these explosions, researchers found signs that cosmic expansion may actually be slowing. They also argue that the apparent acceleration changes with direction, which would be difficult to explain with dark energy. Other cosmologists dispute the conclusion, setting up a major test for upcoming observatories.

Astronomers have detected an exceptionally faint hydrogen radio signal from billions of light-years away using South Africa’s MeerKAT telescope. Instead of finding galaxies one at a time, the technique measures their combined hydrogen glow across enormous stretches of space. The successful detection shows that astronomers may soon be able to create much larger 3D maps of the Universe.

Scientists found that caffeine activates an ancient cellular energy system involved in stress resistance, DNA repair, and growth. The discovery could help explain caffeine’s links to healthier aging and may point toward new ways to target the same pathway.

Researchers discovered that combinations of toxin-blocking proteins naturally found in rattlesnake blood can powerfully neutralize venom from several dangerous snake species. In lab tests, the mixtures were about 10 times more potent than a current commercial antivenom, pointing toward a new generation of nature-inspired snakebite treatments.

More than 1,200 genetic variants have been linked to the Big Five personality traits, and many of the same variants are also associated with health, longevity, careers, income, and everyday habits. The findings reveal a surprisingly wide genetic connection between personality and life outcomes while showing that environment still plays a powerful role.

Semaglutide, the drug behind Ozempic and Wegovy, may have benefits that extend well beyond weight loss and diabetes. In a large Swedish study of nearly 15,000 people with bipolar disorder, its use was linked to a 21% lower risk of psychiatric hospitalization. Researchers think effects on inflammation and brain-related biological pathways could help stabilize mood, though other GLP-1 drugs did not show the same association.

Scientists have identified a giant new dinosaur from Brazil that reached about 20 meters long and lived 120 million years ago. Its surprising evolutionary ties to a Spanish dinosaur suggest its ancestors crossed ancient land connections between Europe, Africa, and South America.

Physicists have directly observed a long-predicted quantum effect of gravity, putting one of Einstein’s foundational ideas to a striking new test. Using ultracold atoms, researchers split an atom’s quantum wave so that one part was held in place while the other fell freely under gravity, then reunited the two to measure the tiny difference that emerged.

The extinct “American cheetah” was not really a cheetah at all, but a puma relative with an unexpectedly flexible lifestyle. Fossils from the Yukon suggest northern populations survived partly by eating fish, possibly including salmon, while southern cats hunted on land.

Researchers have found a potential way to attack prostate cancers that evade treatment by changing their cellular identity. Combining two types of drugs reversed many of these changes and sharply slowed tumor growth in preclinical experiments, offering a possible new strategy for aggressive, treatment-resistant disease.

A critically endangered roloway monkey has given birth just months after surgeons performed an unusual operation that saved her foot from amputation. Her new daughter, Lagertha, is an important addition to a species believed to number fewer than 2,000 in the wild.

A surprising immune system signal may help explain why zebrafish can regenerate damaged spinal cords so effectively. Researchers found that certain neutrophils release Il-4, which calms harmful inflammation and allows injured nerve fibers to grow again. Without these cells, healing stalled, but adding Il-4 restored regeneration. Scientists now want to know whether the same mechanism could someday be harnessed to improve spinal cord repair in humans.