Cambridge scientists have discovered a light-powered chemical reaction that lets researchers modify complex drug molecules at the final stages of development. Unlike traditional methods that rely on toxic chemicals and harsh conditions, the new approach uses an LED lamp to create essential carbon–carbon bonds under mild conditions. This could make drug discovery faster and more environmentally friendly. The breakthrough was uncovered unexpectedly during a failed laboratory experiment.

Scientists have uncovered an enormous hidden archive of plant DNA that has endured for more than 400 million years. By comparing hundreds of plant genomes, researchers identified more than 2.3 million regulatory DNA sequences that act like genetic switches, controlling when and how genes are activated. These sequences, known as conserved non-coding sequences (CNSs), were detected using a new computational tool called Conservatory.

Researchers have identified two gut bacteria that can produce serotonin, a key chemical that regulates bowel movements. In experiments with mice lacking serotonin, the microbes boosted serotonin levels, increased nerve cells in the colon, and normalized intestinal movement. The study also found that people with IBS have lower levels of one of these bacteria. The discovery suggests gut microbes could become a powerful new target for treating digestive disorders.

A newly identified Australian tree has been dubbed the “zombie” tree because it’s alive but unable to reproduce. Myrtle rust repeatedly kills its young growth, stopping the species from flowering or making seeds. Scientists are scrambling to grow disease-free seedlings in protected locations. Their hope is that a future generation may evolve resistance and bring the species back from the brink.

Tiny plastic particles may be quietly threatening brain health. New research suggests microplastics—now widely found in food, water, and even household dust—could trigger inflammation and damage in the brain through multiple biological pathways. Scientists estimate adults may consume about 250 grams of these particles each year, and some can accumulate in organs including the brain.

Scientists are exploring a surprisingly simple way to clean up diesel engines: adding tiny droplets of water to the fuel. During combustion, the water rapidly vaporizes, triggering micro-explosions that improve fuel mixing and lower combustion temperatures. Studies show this technique can slash nitrogen oxide and soot emissions by more than 60% while sometimes even improving engine efficiency. Because it works in existing engines without redesign, it could provide a quick path to cleaner diesel use.

Scientists have uncovered evidence that our Sun may have traveled across the Milky Way as part of a massive migration of Sun-like stars billions of years ago. The journey may have carried the solar system away from the galaxy’s crowded center into a calmer region where life could eventually emerge.

Researchers studying over 8,400 colonoscopies discovered that having both adenomas and serrated polyps in the bowel can raise the risk of serious precancerous changes by up to five times. These two polyp types may represent separate cancer pathways that can occur at the same time. Nearly half of patients with serrated polyps also had adenomas, making this high-risk combination more common than expected. The results emphasize the importance of early detection and regular colonoscopy monitoring.

A severe case of COVID-19 or influenza could increase the risk of lung cancer later on, according to new research. Scientists discovered that serious viral infections can alter immune cells in the lungs, leaving behind chronic inflammation that may help tumors develop months or years later. The increased risk was seen mainly after severe infections that required hospitalization. Vaccination, however, appears to prevent the dangerous lung changes.

In medieval Denmark, people could pay for more prestigious graves closer to the church — a sign of wealth and status. But when researchers examined hundreds of skeletons, they discovered something unexpected: even people with stigmatized diseases like leprosy were buried in these high-status spots. Instead of excluding the sick, many communities appear to have treated them much like everyone else.

Gold and other heavy elements are born in some of the universe’s most violent events—but scientists still struggle to understand the nuclear steps that create them. Now, nuclear physicists have uncovered three key discoveries about how unstable atomic nuclei decay during the rapid neutron-capture process, the chain reaction responsible for forging elements like gold and platinum.

As AI systems began acing traditional tests, researchers realized those benchmarks were no longer tough enough. In response, nearly 1,000 experts created Humanity’s Last Exam, a massive 2,500-question challenge covering highly specialized topics across many fields. The exam was engineered so that any question solvable by current AI models was removed. Early results show even the most advanced systems still struggle — revealing a surprisingly large gap between AI performance and true expert-level knowledge.

Scientists at Arizona State University have uncovered surprising new ways bacteria move, even without their usual whip-like propellers called flagella. In one study, E. coli and salmonella were found to spread across moist surfaces by fermenting sugars and creating tiny fluid currents that carry them forward — a newly identified behavior researchers call “swashing.” In another study, a different group of bacteria was shown to control its movement using a microscopic molecular “gearbox” that can reverse direction like a biological snowmobile.

Scientists have found a promising new way to manufacture one of industry’s toughest materials—tungsten carbide–cobalt—using advanced 3D printing. Normally, producing this ultra-hard material requires high-pressure processes that waste large amounts of expensive tungsten and cobalt. The new approach uses a hot-wire laser technique that softens the metals rather than fully melting them, allowing manufacturers to deposit the material only where it’s needed.

A study from Kobe University has uncovered a surprising partnership between Japanese red elder plants and Heterhelus beetles. The beetles pollinate the flowers but also lay eggs inside the developing fruit. The plant responds by dropping many of those fruits, yet the larvae survive by escaping into the soil. The discovery suggests that fruit drop is not punishment but a compromise that keeps the plant–insect relationship stable.

Researchers have uncovered a universal pattern showing how temperature affects life on Earth. Across thousands of species—from microbes to reptiles—performance rises gradually with warming until an optimal temperature is reached, after which it drops sharply. Although each species has its own preferred temperature range, they all follow the same underlying curve. This surprising constraint suggests evolution may have limited room to help species cope with rapid climate warming.

Scientists analyzing a gravitational-wave signal have discovered that a neutron star and black hole spiraled together on an oval-shaped orbit just before merging. This unusual motion, detected in the event GW200105, contradicts the long-held expectation that such pairs settle into nearly perfect circles before collision. The eccentric orbit suggests the system likely formed in a chaotic stellar environment with strong gravitational interactions.

Researchers have discovered that hedgehogs can hear ultrasound, a surprising ability that could help protect them from cars. Since road traffic kills large numbers of hedgehogs, scientists believe ultrasonic repellents might be used to steer them away from danger. The animals’ ears appear specially adapted for detecting high-frequency sounds. If the idea works, cars could one day emit signals that warn hedgehogs before it’s too late.

Decades of data from over 80,000 great tits reveal that extreme weather can shape the fate of baby birds. Cold snaps soon after hatching and heavy rain later in development shrink nestling body mass and reduce survival odds. But moderate warm spells can actually help chicks grow by boosting insect activity and feeding opportunities. Birds that breed earlier in the season seem better protected from these weather shocks.

Scientists have discovered that a rare “mirror-image” version of the amino acid cysteine can dramatically slow the growth of certain cancers while leaving healthy cells largely untouched. Unlike most anticancer treatments that harm normal tissues, this molecule—called D-cysteine—is taken up mainly by some cancer cells through a specific transporter on their surface. Once inside, it shuts down a crucial mitochondrial enzyme that cancer cells rely on to produce energy and maintain DNA, effectively halting their growth.