❌

Normal view

Received — 14 March 2026 ⏭ Nature - Issue - nature.com science feeds

The dynamic basis of G-protein recognition and activation by a GPCR

Nature, Published online: 11 March 2026; doi:10.1038/s41586-026-10228-w

Conventional and time-resolved cryo-electron microscopy reveal how NTSR1 dynamically engages and releases different G proteins, capturing over 20 intermediates and uncovering key mechanistic steps in GDP- and GTP-driven activation, subtype selectivity and distinct dissociation pathways.

A large-scale coherent 4D imaging sensor

Nature, Published online: 11 March 2026; doi:10.1038/s41586-026-10183-6

A 4D imaging architecture using a large-scale, coherent LiDAR focal plane array comprising more than 0.6 million photonic components and associated electronics integrated on-chip can obtain coherent images at high frame rates over useful distances.
❌