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Received — 8 April 2026 ⏭ Nature Medicine

Nature Medicine
An international mega-analysis of psychedelic drug effects on brain circuit function Manesh Girn · Manoj K. Doss · Leor Roseman · Katrin H. Preller · Fernanda Palhano-Fontes · Lorenzo Pasquini · Frederick S. Barrett · Pablo Mallaroni · Natasha L. Mason · Christopher Timmermann · Drummond E. McCulloch · Patrick M. Fisher · Brian S. Winston · Flora Moujaes · Felix Muller · Matthias E. Liechti · Franz X. Vollenweider · Johannes G. Ramaekers · Kim Kuypers · Draulio B. Araujo · Olaf Sporns · Joshua Siegel · Nico Dosenbach · David J. Nutt · Robin L. Carhart-Harris · Emmanuel A. Stamatakis · Danilo Bzdok
Nature Medicine, Published online: 06 April 2026; doi:10.1038/s41591-026-04287-9Analysis of neuroimaging datasets across five major psychedelics revealed a shared brain signature and provides a comprehensive insight into how these drugs reorganize brain architecture.
6 April 2026 at 08:00

An international mega-analysis of psychedelic drug effects on brain circuit function

6 April 2026 at 08:00

Nature Medicine, Published online: 06 April 2026; doi:10.1038/s41591-026-04287-9

Analysis of neuroimaging datasets across five major psychedelics revealed a shared brain signature and provides a comprehensive insight into how these drugs reorganize brain architecture.