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Received — 2 April 2026 ⏭ npj Digital Medicine

A randomized trial of a digitally delivered, home-based neuromodulation and mindfulness intervention for pain management in older adults with knee osteoarthritis

npj Digital Medicine, Published online: 31 March 2026; doi:10.1038/s41746-026-02577-7

A randomized trial of a digitally delivered, home-based neuromodulation and mindfulness intervention for pain management in older adults with knee osteoarthritis

A unified deep learning framework for cross-platform harmonization of multi-tracer PET quantification in neurodegenerative disease

npj Digital Medicine, Published online: 30 March 2026; doi:10.1038/s41746-026-02570-0

A unified deep learning framework for cross-platform harmonization of multi-tracer PET quantification in neurodegenerative disease
  • ✇npj Digital Medicine
  • Protecting clinical value judgment in the age of AI Shefali V. Patil · Christopher G. Myers · Tinglong Dai
    npj Digital Medicine, Published online: 30 March 2026; doi:10.1038/s41746-026-02561-1Adaptive AI systems embedded in clinical decision-making workflows operationalize hidden value tradeoffs at scale, generating distinct liability pressures and constraining clinicians’ ability to weigh and choose among competing value priorities. To redirect attention from technical model design to procurement and implementation accountability, we propose a collaborative framework: federal mandates for standardiz
     

Protecting clinical value judgment in the age of AI

npj Digital Medicine, Published online: 30 March 2026; doi:10.1038/s41746-026-02561-1

Adaptive AI systems embedded in clinical decision-making workflows operationalize hidden value tradeoffs at scale, generating distinct liability pressures and constraining clinicians’ ability to weigh and choose among competing value priorities. To redirect attention from technical model design to procurement and implementation accountability, we propose a collaborative framework: federal mandates for standardized transparency via Model Cards, paired with internal, multidisciplinary institutional reviews to deliberate and document value-laden configurations.

A multicenter randomized clinical trial of portable transcranial alternating current stimulation for major depressive disorder

npj Digital Medicine, Published online: 28 March 2026; doi:10.1038/s41746-026-02575-9

A multicenter randomized clinical trial of portable transcranial alternating current stimulation for major depressive disorder
Received — 26 March 2026 ⏭ npj Digital Medicine

WiseMind: a knowledge-guided multi-agent framework for accurate and empathetic psychiatric diagnosis

npj Digital Medicine, Published online: 25 March 2026; doi:10.1038/s41746-026-02559-9

WiseMind: a knowledge-guided multi-agent framework for accurate and empathetic psychiatric diagnosis

The untapped potential of ballistographic technology in behavioural sleep medicine

npj Digital Medicine, Published online: 25 March 2026; doi:10.1038/s41746-026-02350-w

Insomnia is the most prevalent sleep disorder globally, for which Cognitive Behavior Therapy for Insomnia (CBT-I) is the first-line treatment. We argue that under-mattress ballistography has the potential to enhance CBT-I delivery by providing treatment-relevant sleep metrics – sleep onset latency, wake after sleep onset, and sleep efficiency, with fewer limitations than polysomnography/actigraphy and consumer-wearable technologies. Validation studies show strong timing accuracy and acceptable sleep–wake classification. Integrating these metrics with CBT-I may improve decision-making, adherence, and outcomes. Future pragmatic trials and validation studies in psychiatric populations are needed.

Effects of multisensory stimulation based on immersive virtual reality in postoperative neuropsychiatric recovery after gynecological laparoscopy

npj Digital Medicine, Published online: 24 March 2026; doi:10.1038/s41746-026-02515-7

Effects of multisensory stimulation based on immersive virtual reality in postoperative neuropsychiatric recovery after gynecological laparoscopy

Boosting foundation models for rare eye disease diagnosis via a multimodal text-to-image generative framework

npj Digital Medicine, Published online: 24 March 2026; doi:10.1038/s41746-026-02560-2

Boosting foundation models for rare eye disease diagnosis via a multimodal text-to-image generative framework
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