Nature Cancer, Published online: 10 March 2026; doi:10.1038/s43018-026-01127-0Kelly et al. assessed an artificial intelligence system for breast cancer screening in retrospective datasets, followed by prospective feasibility evaluation, and report its accuracy, fairness and clinical implementation in multiple workflow settings.

Nature Cancer, Published online: 10 March 2026; doi:10.1038/s43018-026-01128-zWarren et al. used data from a retrospective cohort of 50,000 women attending breast screening. Arbitration between human and AI decisions was performed in a reader study following normal arbitration workflow. After arbitration, replacing the second human reader with AI in a double-read breast screening workflow was noninferior to two human readers.