Nature Biomedical Engineering, Published online: 06 October 2026; doi:10.1038/s41551-026-01786-5A nanoscale metal–organic framework (MOF)-based cancer vaccine platform enables coordinated antigen presentation and innate immune activation, resulting in tumour regression, immune memory and protection against metastasis.

Nature Biomedical Engineering, Published online: 31 August 2026; doi:10.1038/s41551-026-01782-9A protein engineering strategy enables nitric oxide-triggered reactivation of proteins using genetically encoded caged amino acids, allowing inflammation-localized control of protein activity, viral gene delivery and biosensing in vivo.