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Received today — 7 October 2026 ⏭ Nature Biomedical Engineering

Nature Biomedical Engineering
Metal–organic framework nanovaccines for systemic tumour regression Xiaomin Jiang · Chaoyu Wang · Kaiting Yang · Langston Tillman · Elizabeth J. Lin · András Piffkó · Chuangyu Wen · Tomas Germanas · Jinhong Li · Xin Ma · Hua Laura Liang · Ralph R. Weichselbaum · Wenbin Lin
Nature Biomedical Engineering, Published online: 06 October 2026; doi:10.1038/s41551-026-01786-5A nanoscale metal–organic framework (MOF)-based cancer vaccine platform enables coordinated antigen presentation and innate immune activation, resulting in tumour regression, immune memory and protection against metastasis.
6 October 2026 at 08:00

Metal–organic framework nanovaccines for systemic tumour regression

By: Xiaomin Jiang · Chaoyu Wang · Kaiting Yang · Langston Tillman · Elizabeth J. Lin · András Piffkó · Chuangyu Wen · Tomas Germanas · Jinhong Li · Xin Ma · Hua Laura Liang · Ralph R. Weichselbaum · Wenbin Lin

6 October 2026 at 08:00

Nature Biomedical Engineering, Published online: 06 October 2026; doi:10.1038/s41551-026-01786-5

A nanoscale metal–organic framework (MOF)-based cancer vaccine platform enables coordinated antigen presentation and innate immune activation, resulting in tumour regression, immune memory and protection against metastasis.