Nature Biotechnology, Published online: 07 November 2025; doi:10.1038/s41587-025-02941-0Publisher Correction: Deep-learning-based virtual screening of antibacterial compounds

Advances in AI and omics enable the creation of AI virtual cells (AIVCs)—multi-scale, multimodal neural network models that simulate molecules, cells, and tissues across diverse states. This vision outlines their design and collaborative development, promising to transform biological research through high-fidelity simulations, accelerating discoveries, and fostering interdisciplinary open science collaborations.

Nature Biotechnology, Published online: 20 November 2023; doi:10.1038/s41587-023-01988-1Spatial host–microbiome sequencing simultaneously profiles microbes and host transcriptomes from mouse colons.

Nature Biotechnology, Published online: 23 October 2023; doi:10.1038/s41587-023-01964-9Compressed Perturb-seq incorporates compressed sensing to genetic screening for scalable discovery of genetic interactions.

Nature Biotechnology, Published online: 15 September 2022; doi:10.1038/s41587-022-01452-6A mostly natural sequencing-by-synthesis method is effective for scRNA-seq, particularly in large-scale studies.