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cs.AI, q-bio.NC updates on arXiv.org
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Structure-Aware Cooperative Ensemble Evolutionary Optimization on Combinatorial Problems with Multimodal Large Language Models
arXiv:2510.21906v1 Announce Type: cross Abstract: Evolutionary algorithms (EAs) have proven effective in exploring the vast solution spaces typical of graph-structured combinatorial problems. However, traditional encoding schemes, such as binary or numerical representations, often fail to straightforwardly capture the intricate structural properties of networks. Through employing the image-based encoding to preserve topological context, this study utilizes multimodal large language models (MLLM
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Omics In Lung
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RMethyMD: An integrated platform for exploring RNA methylation in pan-cancer via a multiomics analysis
Cancer Lett. 2025 Jan 12;612:217462. doi: 10.1016/j.canlet.2025.217462. Online ahead of print.ABSTRACTA user-friendly integrated database, RMethyMD (http://www.tmliang.cn/rnamethy), was developed to provide a comprehensive analysis of methylation regulators aimed at facilitating the exploration of molecular features in tumorigenesis and clinical implications in cancer diagnosis and treatment via a multiomics approach. Subsequently, molecular landscapes and a robust constructed m6A-based prognost
RMethyMD: An integrated platform for exploring RNA methylation in pan-cancer via a multiomics analysis
Cancer Lett. 2025 Jan 12;612:217462. doi: 10.1016/j.canlet.2025.217462. Online ahead of print.
ABSTRACT
A user-friendly integrated database, RMethyMD (http://www.tmliang.cn/rnamethy), was developed to provide a comprehensive analysis of methylation regulators aimed at facilitating the exploration of molecular features in tumorigenesis and clinical implications in cancer diagnosis and treatment via a multiomics approach. Subsequently, molecular landscapes and a robust constructed m6A-based prognostic model using coxBoost + RSF algorithms in lung cancer highlighted m6A as a suitable marker to guide therapeutic strategy. RMethyMD provides a comprehensive resource and multiomics analysis to explore m6A-based prognostic and clinical values, thereby contributing to aiding personalized cancer therapy.
PMID:39809358 | DOI:10.1016/j.canlet.2025.217462