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Aetheria: A multimodal interpretable content safety framework based on multi-agent debate and collaboration

arXiv:2512.02530v1 Announce Type: new Abstract: The exponential growth of digital content presents significant challenges for content safety. Current moderation systems, often based on single models or fixed pipelines, exhibit limitations in identifying implicit risks and providing interpretable judgment processes. To address these issues, we propose Aetheria, a multimodal interpretable content safety framework based on multi-agent debate and collaboration.Employing a collaborative architecture of five core agents, Aetheria conducts in-depth analysis and adjudication of multimodal content through a dynamic, mutually persuasive debate mechanism, which is grounded by RAG-based knowledge retrieval.Comprehensive experiments on our proposed benchmark (AIR-Bench) validate that Aetheria not only generates detailed and traceable audit reports but also demonstrates significant advantages over baselines in overall content safety accuracy, especially in the identification of implicit risks. This framework establishes a transparent and interpretable paradigm, significantly advancing the field of trustworthy AI content moderation.

MARIA: A Framework for Marginal Risk Assessment without Ground Truth in AI Systems

arXiv:2510.27163v1 Announce Type: cross Abstract: Before deploying an AI system to replace an existing process, it must be compared with the incumbent to ensure improvement without added risk. Traditional evaluation relies on ground truth for both systems, but this is often unavailable due to delayed or unknowable outcomes, high costs, or incomplete data, especially for long-standing systems deemed safe by convention. The more practical solution is not to compute absolute risk but the difference between systems. We therefore propose a marginal risk assessment framework, that avoids dependence on ground truth or absolute risk. It emphasizes three kinds of relative evaluation methodology, including predictability, capability and interaction dominance. By shifting focus from absolute to relative evaluation, our approach equips software teams with actionable guidance: identifying where AI enhances outcomes, where it introduces new risks, and how to adopt such systems responsibly.

AgentArcEval: An Architecture Evaluation Method for Foundation Model based Agents

arXiv:2510.21031v1 Announce Type: cross Abstract: The emergence of foundation models (FMs) has enabled the development of highly capable and autonomous agents, unlocking new application opportunities across a wide range of domains. Evaluating the architecture of agents is particularly important as the architectural decisions significantly impact the quality attributes of agents given their unique characteristics, including compound architecture, autonomous and non-deterministic behaviour, and continuous evolution. However, these traditional methods fall short in addressing the evaluation needs of agent architecture due to the unique characteristics of these agents. Therefore, in this paper, we present AgentArcEval, a novel agent architecture evaluation method designed specially to address the complexities of FM-based agent architecture and its evaluation. Moreover, we present a catalogue of agent-specific general scenarios, which serves as a guide for generating concrete scenarios to design and evaluate the agent architecture. We demonstrate the usefulness of AgentArcEval and the catalogue through a case study on the architecture evaluation of a real-world tax copilot, named Luna.

FieldGen: From Teleoperated Pre-Manipulation Trajectories to Field-Guided Data Generation

arXiv:2510.20774v1 Announce Type: cross Abstract: Large-scale and diverse datasets are vital for training robust robotic manipulation policies, yet existing data collection methods struggle to balance scale, diversity, and quality. Simulation offers scalability but suffers from sim-to-real gaps, while teleoperation yields high-quality demonstrations with limited diversity and high labor cost. We introduce FieldGen, a field-guided data generation framework that enables scalable, diverse, and high-quality real-world data collection with minimal human supervision. FieldGen decomposes manipulation into two stages: a pre-manipulation phase, allowing trajectory diversity, and a fine manipulation phase requiring expert precision. Human demonstrations capture key contact and pose information, after which an attraction field automatically generates diverse trajectories converging to successful configurations. This decoupled design combines scalable trajectory diversity with precise supervision. Moreover, FieldGen-Reward augments generated data with reward annotations to further enhance policy learning. Experiments demonstrate that policies trained with FieldGen achieve higher success rates and improved stability compared to teleoperation-based baselines, while significantly reducing human effort in long-term real-world data collection. Webpage is available at https://fieldgen.github.io/.

NBS1 lactylation is required for efficient DNA repair and chemotherapy resistance

Nature, Published online: 03 July 2024; doi:10.1038/s41586-024-07620-9

Lactylation of NBS1 by TIP60 promotes homologous recombination-driven DNA repair and resistance to chemotherapy in cancer cells and links altered cancer cell metabolism to increase genome stability.
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