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Received — 24 December 2024 ⏭ Favourites

Nature - Issue - nature.com science feeds
Ras drives malignancy through stem cell crosstalk with the microenvironment Shaopeng Yuan · Katherine S. Stewart · Yihao Yang · Merve Deniz Abdusselamoglu · S. Martina Parigi · Tamar Y. Feinberg · Karen Tumaneng · Hanseul Yang · John M. Levorse · Lisa Polak · David Ng · Elaine Fuchs
Nature, Published online: 30 November 2022; doi:10.1038/s41586-022-05475-6Aberrant crosstalk between cancer stem cells and their microenvironment triggers angiogenesis and TGFβ signalling, creating conditions that are conducive for hijacking leptin and leptin receptor signalling, which in turn launches downstream PI3K–AKT–mTOR signalling during the benign-to-malignant transition.
30 November 2022 at 08:00

Ras drives malignancy through stem cell crosstalk with the microenvironment

Nature - Issue - nature.com science feeds

By: Shaopeng Yuan · Katherine S. Stewart · Yihao Yang · Merve Deniz Abdusselamoglu · S. Martina Parigi · Tamar Y. Feinberg · Karen Tumaneng · Hanseul Yang · John M. Levorse · Lisa Polak · David Ng · Elaine Fuchs

30 November 2022 at 08:00

Nature, Published online: 30 November 2022; doi:10.1038/s41586-022-05475-6

Aberrant crosstalk between cancer stem cells and their microenvironment triggers angiogenesis and TGFβ signalling, creating conditions that are conducive for hijacking leptin and leptin receptor signalling, which in turn launches downstream PI3K–AKT–mTOR signalling during the benign-to-malignant transition.