Nature, Published online: 06 March 2024; doi:10.1038/s41586-024-07148-yA meta-analysis of genome-wide association studies for 233 circulating metabolites from 33 cohorts reveals more than 400 loci and suggests probable causal genes, providing insights into metabolic pathways and disease aetiology.

Integrative single-cell RNA sequencing analyses on natural killer (NK) cells from over 700 patients across 24 tumor types depict shared and tumor-type-specific NK cell features and highlight the potential of specific myeloid cell subpopulations in regulating NK cell anti-tumor function.