Nature - Issue - nature.com science feeds
Tumor-selective activity of RAS-GTP inhibition in pancreatic cancer Urszula N. Wasko · Jingjing Jiang · Tanner C. Dalton · Alvaro Curiel-Garcia · A. Cole Edwards · Yingyun Wang · Bianca Lee · Margo Orlen · Sha Tian · Clint A. Stalnecker · Kristina Drizyte-Miller · Marie Menard · Julien Dilly · Stephen A. Sastra · Carmine F. Palermo · Marie C. Hasselluhn · Amanda R. Decker-Farrell · Stephanie Chang · Lingyan Jiang · Xing Wei · Yu C. Yang · Ciara Helland · Haley Courtney · Yevgeniy Gindin · Karl Muonio · Ruiping Zhao · Samantha B. Kemp · Cynthia Clendenin · Rina Sor · William P. Vostrejs · Priya S. Hibshman · Amber M. Amparo · Connor Hennessey · Matthew G. Rees · Melissa M. Ronan · Jennifer A. Roth · Jens Brodbeck · Lorenzo Tomassoni · Basil Bakir · Nicholas D. Socci · Laura E. Herring · Natalie K. Barker · Junning Wang · James M. Cleary · Brian M. Wolpin · John A. Chabot · Michael D. Kluger · Gulam A. Manji · Kenneth Y. Tsai · Miroslav Sekulic · Stephen M. Lagana · Andrea Califano · Elsa Quintana · Zhengping Wang · Jacqueline A. M. Smith · Matthew Holderfield · David Wildes · Scott W. Lowe · Michael A. Badgley · Andrew J. Aguirre · Ro
Nature, Published online: 08 April 2024; doi:10.1038/s41586-024-07379-zTumor-selective activity of RAS-GTP inhibition in pancreatic cancer
8 April 2024 at 08:00

Tumor-selective activity of RAS-GTP inhibition in pancreatic cancer

Nature - Issue - nature.com science feeds

By: Urszula N. Wasko · Jingjing Jiang · Tanner C. Dalton · Alvaro Curiel-Garcia · A. Cole Edwards · Yingyun Wang · Bianca Lee · Margo Orlen · Sha Tian · Clint A. Stalnecker · Kristina Drizyte-Miller · Marie Menard · Julien Dilly · Stephen A. Sastra · Carmine F. Palermo · Marie C. Hasselluhn · Amanda R. Decker-Farrell · Stephanie Chang · Lingyan Jiang · Xing Wei · Yu C. Yang · Ciara Helland · Haley Courtney · Yevgeniy Gindin · Karl Muonio · Ruiping Zhao · Samantha B. Kemp · Cynthia Clendenin · Rina Sor · William P. Vostrejs · Priya S. Hibshman · Amber M. Amparo · Connor Hennessey · Matthew G. Rees · Melissa M. Ronan · Jennifer A. Roth · Jens Brodbeck · Lorenzo Tomassoni · Basil Bakir · Nicholas D. Socci · Laura E. Herring · Natalie K. Barker · Junning Wang · James M. Cleary · Brian M. Wolpin · John A. Chabot · Michael D. Kluger · Gulam A. Manji · Kenneth Y. Tsai · Miroslav Sekulic · Stephen M. Lagana · Andrea Califano · Elsa Quintana · Zhengping Wang · Jacqueline A. M. Smith · Matthew Holderfield · David Wildes · Scott W. Lowe · Michael A. Badgley · Andrew J. Aguirre · Ro

8 April 2024 at 08:00

Nature, Published online: 08 April 2024; doi:10.1038/s41586-024-07379-z

Nature - Issue - nature.com science feeds
7-Dehydrocholesterol dictates ferroptosis sensitivity Yaxu Li · Qiao Ran · Qiuhui Duan · Jiali Jin · Yanjin Wang · Lei Yu · Chaojie Wang · Zhenyun Zhu · Xin Chen · Linjun Weng · Zan Li · Jia Wang · Qi Wu · Hui Wang · Hongling Tian · Sihui Song · Zezhi Shan · Qiwei Zhai · Huanlong Qin · Shili Chen · Lan Fang · Huiyong Yin · Hu Zhou · Xuejun Jiang · Ping Wang
Nature, Published online: 31 January 2024; doi:10.1038/s41586-023-06983-97-Dehydrocholesterol (7-DHC) is a natural anti-ferroptotic metabolite and pharmacological manipulation of 7-DHC levels shows promise as a therapeutic strategy for cancer and ischaemia–reperfusion injury.
31 January 2024 at 08:00

7-Dehydrocholesterol dictates ferroptosis sensitivity

Nature - Issue - nature.com science feeds

By: Yaxu Li · Qiao Ran · Qiuhui Duan · Jiali Jin · Yanjin Wang · Lei Yu · Chaojie Wang · Zhenyun Zhu · Xin Chen · Linjun Weng · Zan Li · Jia Wang · Qi Wu · Hui Wang · Hongling Tian · Sihui Song · Zezhi Shan · Qiwei Zhai · Huanlong Qin · Shili Chen · Lan Fang · Huiyong Yin · Hu Zhou · Xuejun Jiang · Ping Wang

31 January 2024 at 08:00

Nature, Published online: 31 January 2024; doi:10.1038/s41586-023-06983-9

7-Dehydrocholesterol (7-DHC) is a natural anti-ferroptotic metabolite and pharmacological manipulation of 7-DHC levels shows promise as a therapeutic strategy for cancer and ischaemia–reperfusion injury.

Cell Death Discovery nature.com science feeds
Cell death affecting the progression of gastric cancer Haoying Wang · Mengxiao Liu · Xi Zeng · Ya Zheng · Yuping Wang · Yongning Zhou
Cell Death Discovery, Published online: 29 August 2022; doi:10.1038/s41420-022-01161-8Cell death affecting the progression of gastric cancer
29 August 2022 at 08:00

Cell death affecting the progression of gastric cancer

Cell Death Discovery nature.com science feeds

By: Haoying Wang · Mengxiao Liu · Xi Zeng · Ya Zheng · Yuping Wang · Yongning Zhou

29 August 2022 at 08:00

Cell Death Discovery, Published online: 29 August 2022; doi:10.1038/s41420-022-01161-8

Cell death affecting the progression of gastric cancer

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Ovarian cancer (OC) is a highly lethal gynecologic cancer, and it is hard to diagnose at an early stage. Clinically, there are no ovarian cancer-specific markers for early detection. Here, we demonstrate the u...

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