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Predicting disease-free survival in colorectal cancer by circulating tumor DNA methylation markers

Recurrence represents a well-known poor prognostic factor for colorectal cancer (CRC) patients. This study aimed to establish an effective prognostic prediction model based on noninvasive circulating tumor DNA...

Effect of the intratumoral microbiota on spatial and cellular heterogeneity in cancer

Nature, Published online: 16 November 2022; doi:10.1038/s41586-022-05435-0

Spatial profiling and single-cell RNA sequencing are used to map the spatial distribution of the microbiota within human tumours, revealing how intratumoral microbial communities contribute to tumour heterogeneity and cancer progression.
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