❌

Normal view

Large-scale plasma proteomics comparisons through genetics and disease associations

Nature, Published online: 04 October 2023; doi:10.1038/s41586-023-06563-x

Comparisons of phenotypic and genetic association with protein levels from Icelandic and UK Biobank cohorts show that using multiple analysis platforms and stratifying populations by ancestry improves the detection of associations and allows the refinement of their location within the genome.

The sequences of 150,119 genomes in the UK Biobank

Nature, Published online: 20 July 2022; doi:10.1038/s41586-022-04965-x

To measure selection on variants, whole-genome sequencing of approximately 150,000 individuals from the UK Biobank is used to rank sequence variants by their level of depletion.
❌