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Received — 24 December 2024 ⏭ Favourites

NBS1 lactylation is required for efficient DNA repair and chemotherapy resistance

✇Nature - Issue - nature.com science feeds
By: Hengxing Chen · Yun Li · Huafu Li · Xiancong Chen · Huafeng Fu · Deli Mao · Wei Chen · Linxiang Lan · Chunming Wang · Kaishun Hu · Jia Li · Chengming Zhu · Ian Evans · Eddie Cheung · Daning Lu · Yulong He · Axel Behrens · Dong Yin · Changhua Zhang
3 July 2024 at 08:00

Nature, Published online: 03 July 2024; doi:10.1038/s41586-024-07620-9

Lactylation of NBS1 by TIP60 promotes homologous recombination-driven DNA repair and resistance to chemotherapy in cancer cells and links altered cancer cell metabolism to increase genome stability.

Crosstalk between cancer-associated fibroblasts and regulated cell death in tumors: insights into apoptosis, autophagy, ferroptosis, and pyroptosis

✇Cell Death Discovery nature.com science feeds
By: Cong Chen · Jian Liu · Xia Lin · Aizhai Xiang · Qianwei Ye · Jufeng Guo · Tao Rui · Jian Xu · Shufang Hu
22 April 2024 at 08:00

Cell Death Discovery, Published online: 22 April 2024; doi:10.1038/s41420-024-01958-9

Crosstalk between cancer-associated fibroblasts and regulated cell death in tumors: insights into apoptosis, autophagy, ferroptosis, and pyroptosis
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