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A whole-slide foundation model for digital pathology from real-world data

Nature, Published online: 22 May 2024; doi:10.1038/s41586-024-07441-w

Prov-GigaPath, a whole-slide pathology foundation model pretrained on a large dataset containing around 1.3 billion pathology images, attains state-of-the-art performance in cancer classification and pathomics tasks.

7-Dehydrocholesterol dictates ferroptosis sensitivity

Nature, Published online: 31 January 2024; doi:10.1038/s41586-023-06983-9

7-Dehydrocholesterol (7-DHC) is a natural anti-ferroptotic metabolite and pharmacological manipulation of 7-DHC levels shows promise as a therapeutic strategy for cancer and ischaemia–reperfusion injury.

Ferroptosis in lung cancer: a novel pathway regulating cell death and a promising target for drug therapy

Cell Death Discovery, Published online: 01 April 2023; doi:10.1038/s41420-023-01407-z

Ferroptosis in lung cancer: a novel pathway regulating cell death and a promising target for drug therapy
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