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Received — 24 December 2024 ⏭ Favourites

Cell
Multiscale drug screening for cardiac fibrosis identifies MD2 as a therapeutic target Hao Zhang · Phung N. Thai · Rabindra V. Shivnaraine · Lu Ren · Xuekun Wu · Dirk H. Siepe · Yu Liu · Chengyi Tu · Hye Sook Shin · Arianne Caudal · Souhrid Mukherjee · Jeremy Leitz · Wilson Tan Lek Wen · Wenqiang Liu · Wenjuan Zhu · Nipavan Chiamvimonvat · Joseph C. Wu
A multiscale drug discovery platform integrating human induced pluripotent stem cells, 3D-engineered heart tissues, and animal models identifies artesunate as a safe and potent antifibrotic compound.
15 October 2024 at 08:00

Multiscale drug screening for cardiac fibrosis identifies MD2 as a therapeutic target

Cell

By: Hao Zhang · Phung N. Thai · Rabindra V. Shivnaraine · Lu Ren · Xuekun Wu · Dirk H. Siepe · Yu Liu · Chengyi Tu · Hye Sook Shin · Arianne Caudal · Souhrid Mukherjee · Jeremy Leitz · Wilson Tan Lek Wen · Wenqiang Liu · Wenjuan Zhu · Nipavan Chiamvimonvat · Joseph C. Wu

15 October 2024 at 08:00

A multiscale drug discovery platform integrating human induced pluripotent stem cells, 3D-engineered heart tissues, and animal models identifies artesunate as a safe and potent antifibrotic compound.