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Normal view

OTUB1/NDUFS2 axis promotes pancreatic tumorigenesis through protecting against mitochondrial cell death

Cell Death Discovery, Published online: 23 April 2024; doi:10.1038/s41420-024-01948-x

OTUB1/NDUFS2 axis promotes pancreatic tumorigenesis through protecting against mitochondrial cell death

Nuclear export of circular RNA

Nature, Published online: 14 February 2024; doi:10.1038/s41586-024-07060-5

Circular RNAs are exported from the nucleus by Ran-GTP, exportin-2 and IGF2BP1 in a mechanism analogous to protein export rather than mRNA export.

A multi-tissue metabolome atlas of primate pregnancy

A multi-tissue metabolome atlas of 23 maternal tissues from pregnant monkeys revealed dynamic metabolic coupling, core pathways, and a multitude of pregnancy-adaptive metabolites during normal primate pregnancy, with implications for female health.

A draft human pangenome reference

Nature, Published online: 10 May 2023; doi:10.1038/s41586-023-05896-x

An initial draft of the human pangenome is presented and made publicly available by the Human Pangenome Reference Consortium; the draft contains 94 de novo haplotype assemblies from 47 ancestrally diverse individuals.
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