Cell Death Discovery nature.com science feeds
KDM5B promotes SMAD4 loss-driven drug resistance through activating DLG1/YAP to induce lipid accumulation in pancreatic ductal adenocarcinoma Yumin Wang · Shiqian Liu · Yan Wang · Baibei Li · Jiaming Liang · Yu Chen · Bo Tang · Shuiping Yu · Hongquan Wang
Cell Death Discovery, Published online: 24 May 2024; doi:10.1038/s41420-024-02020-4KDM5B promotes SMAD4 loss-driven drug resistance through activating DLG1/YAP to induce lipid accumulation in pancreatic ductal adenocarcinoma
24 May 2024 at 08:00

KDM5B promotes SMAD4 loss-driven drug resistance through activating DLG1/YAP to induce lipid accumulation in pancreatic ductal adenocarcinoma

Cell Death Discovery nature.com science feeds

By: Yumin Wang · Shiqian Liu · Yan Wang · Baibei Li · Jiaming Liang · Yu Chen · Bo Tang · Shuiping Yu · Hongquan Wang

24 May 2024 at 08:00

Cell Death Discovery, Published online: 24 May 2024; doi:10.1038/s41420-024-02020-4

Nature - Issue - nature.com science feeds
Deep whole-genome analysis of 494 hepatocellular carcinomas Lei Chen · Chong Zhang · Ruidong Xue · Mo Liu · Jian Bai · Jinxia Bao · Yin Wang · Nanhai Jiang · Zhixuan Li · Wenwen Wang · Ruiru Wang · Bo Zheng · Airong Yang · Ji Hu · Ke Liu · Siyun Shen · Yangqianwen Zhang · Mixue Bai · Yan Wang · Yanjing Zhu · Shuai Yang · Qiang Gao · Jin Gu · Dong Gao · Xin Wei Wang · Hidewaki Nakagawa · Ning Zhang · Lin Wu · Steven G. Rozen · Fan Bai · Hongyang Wang
Nature, Published online: 14 February 2024; doi:10.1038/s41586-024-07054-3The Chinese Liver Cancer Atlas project depicts a panoramic genomic landscape of hepatocellular carcinoma, covering candidate coding and non-coding drivers, mutational signatures, extrachromosomal circular DNA, subclonal catastrophic events and detailed evolutionary history.
14 February 2024 at 08:00

Deep whole-genome analysis of 494 hepatocellular carcinomas

Nature - Issue - nature.com science feeds

By: Lei Chen · Chong Zhang · Ruidong Xue · Mo Liu · Jian Bai · Jinxia Bao · Yin Wang · Nanhai Jiang · Zhixuan Li · Wenwen Wang · Ruiru Wang · Bo Zheng · Airong Yang · Ji Hu · Ke Liu · Siyun Shen · Yangqianwen Zhang · Mixue Bai · Yan Wang · Yanjing Zhu · Shuai Yang · Qiang Gao · Jin Gu · Dong Gao · Xin Wei Wang · Hidewaki Nakagawa · Ning Zhang · Lin Wu · Steven G. Rozen · Fan Bai · Hongyang Wang

14 February 2024 at 08:00

Nature, Published online: 14 February 2024; doi:10.1038/s41586-024-07054-3

The Chinese Liver Cancer Atlas project depicts a panoramic genomic landscape of hepatocellular carcinoma, covering candidate coding and non-coding drivers, mutational signatures, extrachromosomal circular DNA, subclonal catastrophic events and detailed evolutionary history.

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Ovarian cancer (OC) is a highly lethal gynecologic cancer, and it is hard to diagnose at an early stage. Clinically, there are no ovarian cancer-specific markers for early detection. Here, we demonstrate the u...
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Detection of ovarian cancer using plasma cell-free DNA methylomes

Most Recent Articles: Clinical Epigenetics

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Ovarian cancer (OC) is a highly lethal gynecologic cancer, and it is hard to diagnose at an early stage. Clinically, there are no ovarian cancer-specific markers for early detection. Here, we demonstrate the u...

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