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KDM5B promotes SMAD4 loss-driven drug resistance through activating DLG1/YAP to induce lipid accumulation in pancreatic ductal adenocarcinoma

Cell Death Discovery, Published online: 24 May 2024; doi:10.1038/s41420-024-02020-4

KDM5B promotes SMAD4 loss-driven drug resistance through activating DLG1/YAP to induce lipid accumulation in pancreatic ductal adenocarcinoma

A draft human pangenome reference

Nature, Published online: 10 May 2023; doi:10.1038/s41586-023-05896-x

An initial draft of the human pangenome is presented and made publicly available by the Human Pangenome Reference Consortium; the draft contains 94 de novo haplotype assemblies from 47 ancestrally diverse individuals.

Semi-automated assembly of high-quality diploid human reference genomes

Nature, Published online: 19 October 2022; doi:10.1038/s41586-022-05325-5

Which combination of current genome sequencing and assembly approaches results in high-quality, complete diploid genome assemblies is determined.
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