Nature, Published online: 23 December 2024; doi:10.1038/s41586-024-08555-xAuthor Correction: π-HuB: the proteomic navigator of the human body

Cancer is a systemic disease in more than one dimension, in terms of its evolutionary course, direct crosstalk with the microenvironment, and intricate communication with the macro-environment. This broad perspective encompasses our understanding of cancer’s systemic features, mapping out the path for tackling its complexity to bridge what we can learn and who we need to help.

Cancer biomarkers have transformed oncology, enabling treatments tailored to each tumor’s unique profile. This review highlights the field’s progress due to advancements in understanding cancer biology, testing methods, and understanding of the immune microenvironment to advance precision oncology for improved patient outcomes.

Nature, Published online: 27 March 2024; doi:10.1038/s41586-024-07239-wWe introduce multinucleic acid interaction mapping in single cells (MUSIC), for concurrent profiling of multiplex chromatin interactions, gene expression and RNA–chromatin associations within individual nuclei, as a tool for exploring chromatin architecture and transcription.

Nature, Published online: 08 February 2024; doi:10.1038/s41586-024-07051-6Author Correction: Genotyping, sequencing and analysis of 140,000 adults from Mexico City

Nature, Published online: 18 December 2023; doi:10.1038/s41586-023-06961-1Publisher Correction: Slide-tags enables single-nucleus barcoding for multimodal spatial genomics

Nature, Published online: 13 December 2023; doi:10.1038/s41586-023-06837-4Slide-tags enables multiomic sequencing of single cells and their localization within tissues.

Nature Biotechnology, Published online: 06 February 2023; doi:10.1038/s41587-022-01652-0A six-letter sequencing workflow can simultaneously detect genetic and epigenetic bases.

Over the past decade, bioethicists, legal scholars and social scientists have started to investigate the potential implications of epigenetic research and technologies on medicine and society. There is growing...

African Americans have a high risk for type 2 diabetes (T2D) and insulin resistance. Studies among other population groups have identified DNA methylation loci associated with insulin resistance, but data in A...

We tested the ability of a novel DNA methylation biomarker set to distinguish metastatic pancreatic cancer cases from benign pancreatic cyst patients and to monitor tumor dynamics using quantitative DNA methyl...