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Received — 7 November 2025 ⏭ Favourites

Nature Biotechnology - Issue - nature.com science feeds
Site-specific DNA insertion into the human genome with engineered recombinases Alison Fanton · Liam J. Bartie · Juliana Q. Martins · Vincent Q. Tran · Laine Goudy · Courtney Kernick · Matthew G. Durrant · Jingyi Wei · Zev Armour-Garb · April Pawluk · Silvana Konermann · Alexander Marson · Luke A. Gilbert · Theodore L. Roth · Patrick D. Hsu
Nature Biotechnology, Published online: 06 November 2025; doi:10.1038/s41587-025-02895-3Engineered DNA recombinases efficiently and specifically insert genetic cargos without the use of landing pads.
6 November 2025 at 08:00

Site-specific DNA insertion into the human genome with engineered recombinases

Nature Biotechnology - Issue - nature.com science feeds

By: Alison Fanton · Liam J. Bartie · Juliana Q. Martins · Vincent Q. Tran · Laine Goudy · Courtney Kernick · Matthew G. Durrant · Jingyi Wei · Zev Armour-Garb · April Pawluk · Silvana Konermann · Alexander Marson · Luke A. Gilbert · Theodore L. Roth · Patrick D. Hsu

6 November 2025 at 08:00

Nature Biotechnology, Published online: 06 November 2025; doi:10.1038/s41587-025-02895-3

Engineered DNA recombinases efficiently and specifically insert genetic cargos without the use of landing pads.