Normal view
-
cs.AI, q-bio.NC updates on arXiv.org
-
Cognitive bias in LLM reasoning compromises interpretation of clinical oncology notes
arXiv:2511.20680v1 Announce Type: cross Abstract: Despite high performance on clinical benchmarks, large language models may reach correct conclusions through faulty reasoning, a failure mode with safety implications for oncology decision support that is not captured by accuracy-based evaluation. In this two-cohort retrospective study, we developed a hierarchical taxonomy of reasoning errors from GPT-4 chain-of-thought responses to real oncology notes and tested its clinical relevance. Using br
-
cs.AI, q-bio.NC updates on arXiv.org
-
How Do Companies Manage the Environmental Sustainability of AI? An Interview Study About Green AI Efforts and Regulations
arXiv:2505.07317v2 Announce Type: replace-cross Abstract: With the ever-growing adoption of artificial intelligence (AI), AI-based software and its negative impact on the environment are no longer negligible, and studying and mitigating this impact has become a critical area of research. However, it is currently unclear which role environmental sustainability plays during AI adoption in industry and how AI regulations influence Green AI practices and decision-making in industry. We therefore ai
How Do Companies Manage the Environmental Sustainability of AI? An Interview Study About Green AI Efforts and Regulations
-
(Multiomics OR Omics) AND (Lung OR gastric OR Hepatocellular)
-
scGALA advances graph link prediction-based cell alignment for comprehensive data integration and harmonization
Nat Commun. 2025 Nov 26. doi: 10.1038/s41467-025-66644-5. Online ahead of print.ABSTRACTSingle-cell technologies have transformed our understanding of cellular heterogeneity through multimodal data acquisition. However, robust cell alignment remains a major challenge for data integration and harmonization, including batch correction, label transfer, and multi-omics integration. Many existing methods constrain alignment based on rigid feature-wise distance metrics, limiting their ability to captu
scGALA advances graph link prediction-based cell alignment for comprehensive data integration and harmonization
Nat Commun. 2025 Nov 26. doi: 10.1038/s41467-025-66644-5. Online ahead of print.
ABSTRACT
Single-cell technologies have transformed our understanding of cellular heterogeneity through multimodal data acquisition. However, robust cell alignment remains a major challenge for data integration and harmonization, including batch correction, label transfer, and multi-omics integration. Many existing methods constrain alignment based on rigid feature-wise distance metrics, limiting their ability to capture accurate cell correspondence across diverse cell populations and conditions. We introduce scGALA, a graph-based learning framework that redefines cell alignment by combining graph attention networks with a score-driven, task-independent optimization strategy. scGALA constructs enriched graphs of cell-cell relationships by integrating gene expression profiles with auxiliary information, such as spatial coordinates, and iteratively refines alignment via self-supervised graph link prediction, where a deep neural network is trained to identify and reinforce high-confidence correspondences across datasets. In extensive benchmarks, scGALA identifies over 25 percent more high-confidence alignments without compromising accuracy. By improving the core step of cell alignment, scGALA serves as a versatile enhancer for a wide range of single-cell data integration tasks.
PMID:41298467 | DOI:10.1038/s41467-025-66644-5