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Normal view

A nowhere-to-hide mechanism ensures complete piRNA-directed DNA methylation

Nature, Published online: 14 January 2026; doi:10.1038/s41586-025-09940-w

In mice, a SPOCD1–TPR-dependent ‘nowhere-to-hide’ mechanism is required for complete non-stochastic piRNA-directed LINE1 DNA methylation by preventing transposons from escaping surveillance within heterochromatin.

Enhancing telesurgical safety with predictive digital twin synchronization: a framework for latency compensation in robotic surgery

npj Digital Medicine, Published online: 13 January 2026; doi:10.1038/s41746-025-02283-w

Enhancing telesurgical safety with predictive digital twin synchronization: a framework for latency compensation in robotic surgery
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