Normal view

Received — 27 May 2026 ⏭

Cell
Proteostasis sustains T cell differentiation potential and tumor-infiltrating lymphocyte function Nicole E. Scharping · Xuezhen Ge · Maria Inês Matias · Fulin Jiang · Allison Cafferata · Maximilian Heeg · Alexander Monell · Giovanni Galletti · Kitty P. Cheung · Angelica Rock · Nick Thao · Sydnye L. Shuttleworth · Michael A. Bauer · Kennidy K. Takehara · Amir Ferry · Sara Quon · Brian Koss · Samuel A. Myers · Eric J. Bennett · Ananda W. Goldrath
Exhausted T cells experience a breakdown of proteostasis, characterized by unfolded protein accumulation and rescuable by E3 ubiquitin ligase activity. Targeting T cell proteostasis highlights a promising strategy for cancer immunotherapy.
29 April 2026 at 08:00

Proteostasis sustains T cell differentiation potential and tumor-infiltrating lymphocyte function

Cell

By: Nicole E. Scharping · Xuezhen Ge · Maria Inês Matias · Fulin Jiang · Allison Cafferata · Maximilian Heeg · Alexander Monell · Giovanni Galletti · Kitty P. Cheung · Angelica Rock · Nick Thao · Sydnye L. Shuttleworth · Michael A. Bauer · Kennidy K. Takehara · Amir Ferry · Sara Quon · Brian Koss · Samuel A. Myers · Eric J. Bennett · Ananda W. Goldrath

29 April 2026 at 08:00

Exhausted T cells experience a breakdown of proteostasis, characterized by unfolded protein accumulation and rescuable by E3 ubiquitin ligase activity. Targeting T cell proteostasis highlights a promising strategy for cancer immunotherapy.

Received — 13 April 2026 ⏭

Author Correction: Multi-omic profiling reveals age-related immune dynamics in healthy adults

Nature - Issue - nature.com science feeds

By: Qiuyu Gong · Mehul Sharma · Marla C. Glass · Emma L. Kuan · Aishwarya Chander · Mansi Singh · Lucas T. Graybuck · Zachary J. Thomson · Christian M. LaFrance · Samir Rachid Zaim · Tao Peng · Lauren Y. Okada · Palak C. Genge · Katherine E. Henderson · Elisabeth M. Dornisch · Erik D. Layton · Peter J. Wittig · Alexander T. Heubeck · Nelson M. Mukuka · Julian Reading · Garrett Strawn · Teminijesu Titus-Adewunmi · Kathleen Abadie · Charles R. Roll · Veronica Hernandez · Vaishnavi Parthasarathy · Tyanna J. Stuckey · Blessing Musgrove · Elliott Swanson · Cara Lord · Morgan D. A. Weiss · Cole G. Phalen · Regina R. Mettey · Kevin J. Lee · John B. Johanneson · Erin K. Kawelo · Jessica Garber · Upaasana Krishnan · Megan Smithmyer · E. John Wherry · Laura A. Vella · Sarah E. Henrickson · Mackenzie S. Kopp · Adam K. Savage · Lynne A. Becker · Paul Meijer · Ernest M. Coffey · Jorg J. Goronzy · Mikael Sigvardsson · Cate Speake · Thomas F. Bumol · Ananda W. Goldrath · Troy R. Torgerson · Xiao-jun Li · Peter J. Skene · Jane H. Buckner · Claire E. Gustafson

10 April 2026 at 08:00

Nature, Published online: 10 April 2026; doi:10.1038/s41586-026-10484-w

Author Correction: Multi-omic profiling reveals age-related immune dynamics in healthy adults