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TA-RNN-Medical-Hybrid: A Time-Aware and Interpretable Framework for Mortality Risk Prediction

arXiv:2603.08278v1 Announce Type: cross Abstract: Accurate and interpretable mortality risk prediction in intensive care units (ICUs) remains a critical challenge due to the irregular temporal structure of electronic health records (EHRs), the complexity of longitudinal disease trajectories, and the lack of clinically grounded explanations in many data-driven models. To address these challenges, we propose \textit{TA-RNN-Medical-Hybrid}, a time-aware and knowledge-enriched deep learning framework that jointly models longitudinal clinical sequences and irregular temporal dynamics through explicit continuous-time encoding, along with standardized medical concept representations. The proposed framework extends time-aware recurrent modeling by integrating explicit continuous-time embeddings that operate independently of visit indexing, SNOMED-based disease representations, and a hierarchical dual-level attention mechanism that captures both visit-level temporal importance and feature/concept-level clinical relevance. This design enables accurate mortality risk estimation while providing transparent and clinically meaningful explanations aligned with established medical knowledge. We evaluate the proposed approach on the MIMIC-III critical care dataset and compare it against strong time-aware and sequential baselines. Experimental results demonstrate that TA-RNN-Medical-Hybrid consistently improves predictive performance in terms of AUC, accuracy, and recall-oriented F$_2$-score. Moreover, qualitative analysis shows that the model effectively decomposes mortality risk across time and clinical concepts, yielding interpretable insights into disease severity, chronicity, and temporal progression. Overall, the proposed framework bridges the gap between predictive accuracy and clinical interpretability, offering a scalable and transparent solution for high-stakes ICU decision support systems.

Deep Reinforcement Learning for Optimizing Energy Consumption in Smart Grid Systems

arXiv:2602.18531v1 Announce Type: cross Abstract: The energy management problem in the context of smart grids is inherently complex due to the interdependencies among diverse system components. Although Reinforcement Learning (RL) has been proposed for solving Optimal Power Flow (OPF) problems, the requirement for iterative interaction with an environment often necessitates computationally expensive simulators, leading to significant sample inefficiency. In this study, these challenges are addressed through the use of Physics-Informed Neural Networks (PINNs), which can replace conventional and costly smart grid simulators. The RL policy learning process is enhanced so that convergence can be achieved in a fraction of the time required by the original environment. The PINN-based surrogate is compared with other benchmark data-driven surrogate models. By incorporating knowledge of the underlying physical laws, the results show that the PINN surrogate is the only approach considered in this context that can obtain a strong RL policy even without access to samples from the true simulator. The results demonstrate that using PINN surrogates can accelerate training by 50% compared to RL training without a surrogate. This approach enables the rapid generation of performance scores similar to those produced by the original simulator.
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