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Received — 2 April 2026 ⏭

Nature - Issue - nature.com science feeds
DNA damage burden causes selective CUX2 neuron loss in neuroinflammation Laura Morcom · Wenlong Xia · Zhaoyang Xu · Yashika Awasthi · Celine Geywitz · Matthew O. Ellis · Tomas Noli · Amel Zulji · Daniel Yamamoto · Gemma C. Girdler · Li Kai · Keying Zhu · Mingming Wei · Xiao-Yan Tang · Kimberly K. Hoi · Julio Gonzalez-Maya · Greg J. Duncan · Adrien M. Vaquie · Diana Gold Diaz · Riki Kawaguchi · Erdong Liu · Yu Sun · Denny Yang · Gregory D. Jordan · I-Ling Lu · Staffan Holmqvist · Theresa Bartels · Katherine Ridley · Jennifer Ja-Yoon Choi · Santos J. Franco · Eric J. Huang · Ben Emery · Daniel Geschwind · Lucas Schirmer · Gabriel Balmus · Brian Popko · Stephen P. J. Fancy · David H. Rowitch
Nature, Published online: 01 April 2026; doi:10.1038/s41586-026-10310-3DNA damage burden and inadequate repair in CUX2+ cortical layer 2/3 excitatory neurons contributes to selective vulnerability in neuroinflammatory injury.
1 April 2026 at 08:00

DNA damage burden causes selective CUX2 neuron loss in neuroinflammation

Nature - Issue - nature.com science feeds

By: Laura Morcom · Wenlong Xia · Zhaoyang Xu · Yashika Awasthi · Celine Geywitz · Matthew O. Ellis · Tomas Noli · Amel Zulji · Daniel Yamamoto · Gemma C. Girdler · Li Kai · Keying Zhu · Mingming Wei · Xiao-Yan Tang · Kimberly K. Hoi · Julio Gonzalez-Maya · Greg J. Duncan · Adrien M. Vaquie · Diana Gold Diaz · Riki Kawaguchi · Erdong Liu · Yu Sun · Denny Yang · Gregory D. Jordan · I-Ling Lu · Staffan Holmqvist · Theresa Bartels · Katherine Ridley · Jennifer Ja-Yoon Choi · Santos J. Franco · Eric J. Huang · Ben Emery · Daniel Geschwind · Lucas Schirmer · Gabriel Balmus · Brian Popko · Stephen P. J. Fancy · David H. Rowitch

1 April 2026 at 08:00

Nature, Published online: 01 April 2026; doi:10.1038/s41586-026-10310-3

DNA damage burden and inadequate repair in CUX2+ cortical layer 2/3 excitatory neurons contributes to selective vulnerability in neuroinflammatory injury.