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Received — 14 March 2026 ⏭

B cell imprinting in children impairs antibodies to the haemagglutinin stalk

✇Nature - Issue - nature.com science feeds
By: Jiayi Sun · Gyunghee Jo · Chloe A. Troxell · Yanbin Fu · Robert Hoezl · Huibin Lv · Hassanein H. Abozeid · Qi Wen Teo · Tossapol Pholcharee · Joshua J. C. McGrath · Siriruk Changrob · Sean A. Nelson · Atsuhiro Yasuhara · Min Huang · Nai-Ying Zheng · Jordan C. Chervin · Lei Li · Monica L. Fernández-Quintero · Johannes R. Loeffler · Alesandra J. Rodriguez · Jiachen Huang · Olivia M. Swanson · Angel Balmaseda · Guillermina Kuan · Lora Campredon · E. Kaitlynn Allen · Gabriele Neumann · Nicholas C. Wu · Yoshihiro Kawaoka · Florian Krammer · Asuncion Mejias · Octavio Ramilo · Paul G. Thomas · Aubree Gordon · Andrew B. Ward · Julianna Han · Patrick C. Wilson
11 March 2026 at 08:00

Nature, Published online: 11 March 2026; doi:10.1038/s41586-026-10248-6

Imprinting by influenza viruses can cause a deleterious shift of nearly the entire memory recall response against key, conserved epitopes.
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