Normal view
-
cs.AI, q-bio.NC updates on arXiv.org
-
RAU: Reference-based Anatomical Understanding with Vision Language Models
arXiv:2509.22404v2 Announce Type: replace-cross Abstract: Anatomical understanding, which is the ability to identify, localize, or segment anatomical structures, is critical in medical image analysis; however, its progress is constrained by the scarcity of expert-labeled data. A promising remedy is to leverage an annotated reference image to guide the interpretation of an unlabeled target. Although recent vision-language models (VLMs) exhibit non-trivial visual reasoning, their reference-based
-
Nature - Issue - nature.com science feeds
-
Denisovans from southwestern China and their subsistence strategies
Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-10997-4Evidence from Bianfu Cave shows specialized hunting, expedient stone-tool production and extensive bone use of Denisovans, providing new insights into their ecology, behaviour and cultural legacy in eastern Asia.
Denisovans from southwestern China and their subsistence strategies
Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-10997-4
Evidence from Bianfu Cave shows specialized hunting, expedient stone-tool production and extensive bone use of Denisovans, providing new insights into their ecology, behaviour and cultural legacy in eastern Asia.-
Pulmonary nodule
-
Proteomic and lipidomic analyses reveal molecular subtypes and potential targets in early-stage lung adenocarcinoma among non-smokers
Cell Rep. 2026 May 26;45(5):117215. doi: 10.1016/j.celrep.2026.117215. Epub 2026 Apr 28.ABSTRACTEarly-stage lung adenocarcinoma (LUAD) in never smokers exhibits distinct biological features, yet the metabolic programs driving early invasion remain unclear. We integrate proteomic and lipidomic profiling of primary LUAD tumors from never smokers, matched normal adjacent tissues (NATs), and benign pulmonary nodules (BPNs). Integrated multi-omics analysis reveals coordinated dysregulation of lipid m
Proteomic and lipidomic analyses reveal molecular subtypes and potential targets in early-stage lung adenocarcinoma among non-smokers
Cell Rep. 2026 May 26;45(5):117215. doi: 10.1016/j.celrep.2026.117215. Epub 2026 Apr 28.
ABSTRACT
Early-stage lung adenocarcinoma (LUAD) in never smokers exhibits distinct biological features, yet the metabolic programs driving early invasion remain unclear. We integrate proteomic and lipidomic profiling of primary LUAD tumors from never smokers, matched normal adjacent tissues (NATs), and benign pulmonary nodules (BPNs). Integrated multi-omics analysis reveals coordinated dysregulation of lipid metabolism and immune signaling in early LUAD. Proteome-based network fusion stratifies invasive LUAD into immune-metabolic synergistic (IMS) and metabolic-stress-driven (MSD) subtypes. IMS tumors retain apolipoprotein-associated lipid modules and favorable immune features, whereas MSD tumors exhibit stress-response programs. Mechanistically, APOA1 and APOC1 emerge as key nodes linking lipid homeostasis to invasion, and their depletion promotes LUAD cell migration and invasion. We establish a two-protein, four-lipid diagnostic panel demonstrating robust performance across tissue and plasma cohorts. These findings provide a molecular basis for early detection and risk stratification in never smokers.
PMID:42054209 | DOI:10.1016/j.celrep.2026.117215
-
cs.AI, q-bio.NC updates on arXiv.org
-
UniAI-GraphRAG: Synergizing Ontology-Guided Extraction, Multi-Dimensional Clustering, and Dual-Channel Fusion for Robust Multi-Hop Reasoning
arXiv:2603.25152v2 Announce Type: replace Abstract: Retrieval-Augmented Generation (RAG) systems face significant challenges in complex reasoning, multi-hop queries, and domain-specific QA. While existing GraphRAG frameworks have made progress in structural knowledge organization, they still have limitations in cross-industry adaptability, community report integrity, and retrieval performance. This paper proposes UniAI-GraphRAG, an enhanced framework built upon open-source GraphRAG. The framewo
UniAI-GraphRAG: Synergizing Ontology-Guided Extraction, Multi-Dimensional Clustering, and Dual-Channel Fusion for Robust Multi-Hop Reasoning
-
cs.AI, q-bio.NC updates on arXiv.org
-
$V_0$: A Generalist Value Model for Any Policy at State Zero
arXiv:2602.03584v2 Announce Type: replace-cross Abstract: Policy gradient methods rely on a baseline to measure the relative advantage of an action, ensuring the model reinforces behaviors that outperform its current average capability. In the training of Large Language Models (LLMs) using Actor-Critic methods (e.g., PPO), this baseline is typically estimated by a Value Model (Critic) often as large as the policy model itself. However, as the policy continuously evolves, the value model require
$V_0$: A Generalist Value Model for Any Policy at State Zero
-
cs.AI, q-bio.NC updates on arXiv.org
-
REVISION:Reflective Intent Mining and Online Reasoning Auxiliary for E-commerce Visual Search System Optimization
arXiv:2510.22739v2 Announce Type: replace-cross Abstract: In Taobao e-commerce visual search, user behavior analysis reveals a large proportion of no-click requests, suggesting diverse and implicit user intents. These intents are expressed in various forms and are difficult to mine and discover, thereby leading to the limited adaptability and lag in platform strategies. This greatly restricts users' ability to express diverse intents and hinders the scalability of the visual search system. This
REVISION:Reflective Intent Mining and Online Reasoning Auxiliary for E-commerce Visual Search System Optimization
-
cs.AI, q-bio.NC updates on arXiv.org
-
MemOCR: Layout-Aware Visual Memory for Efficient Long-Horizon Reasoning
arXiv:2601.21468v3 Announce Type: replace Abstract: Long-horizon agentic reasoning necessitates effectively compressing growing interaction histories into a limited context window. Most existing memory systems serialize history as text, where token-level cost is uniform and scales linearly with length, often spending scarce budget on low-value details. To this end, we introduce MemOCR, a multimodal memory agent that improves long-horizon reasoning under tight context budgets by allocating memor