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cs.AI, q-bio.NC updates on arXiv.org
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SelfGrader: Stable Jailbreak Detection for Large Language Models using Token-Level Logits
arXiv:2604.01473v1 Announce Type: cross Abstract: Large Language Models (LLMs) are powerful tools for answering user queries, yet they remain highly vulnerable to jailbreak attacks. Existing guardrail methods typically rely on internal features or textual responses to detect malicious queries, which either introduce substantial latency or suffer from the randomness in text generation. To overcome these limitations, we propose SelfGrader, a lightweight guardrail method that formulates jailbreak
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MRD
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Surgery-centered integrated strategies for personalized hepatocellular carcinoma care
Cancer Biol Med. 2026 Mar 30:j.issn.2095-3941.2026.0045. doi: 10.20892/j.issn.2095-3941.2026.0045. Online ahead of print.ABSTRACTHepatocellular carcinoma (HCC) remains a major global health burden characterized by late-stage diagnosis and high postoperative recurrence rates. This review presents a surgery-centered precision management framework integrating 3 synergistic components: early detection, precision surgery, and recurrence prevention. Early detection strategies incorporate multiparamete
Surgery-centered integrated strategies for personalized hepatocellular carcinoma care
Cancer Biol Med. 2026 Mar 30:j.issn.2095-3941.2026.0045. doi: 10.20892/j.issn.2095-3941.2026.0045. Online ahead of print.
ABSTRACT
Hepatocellular carcinoma (HCC) remains a major global health burden characterized by late-stage diagnosis and high postoperative recurrence rates. This review presents a surgery-centered precision management framework integrating 3 synergistic components: early detection, precision surgery, and recurrence prevention. Early detection strategies incorporate multiparameter risk models including the gender, age, AFP-L3, AFP, and DCP (GALAD) as well as age, sex, AFP, and PIVKA-II (ASAP) scores, alongside circulating tumor DNA methylation-based liquid biopsy, thus enabling tumor identification at stages amenable to curative resection. Precision surgery optimizes patient selection through refined staging systems including the Chinese liver cancer staging (CNLC), and functional assessments including the albumin-bilirubin (ALBI) grade, whereas conversion therapy and minimally invasive approaches extend surgical eligibility to selected patients with intermediate-stage disease. To mitigate the risk of postoperative recurrence, distinguishing between early and late recurrence patterns and monitoring minimal residual disease are critical strategies. Perioperative systemic therapies, particularly immune checkpoint inhibitor-based combinations, show promise for eradicating micrometastatic disease. This integrated framework provides a cohesive, evidence-based approach to personalized HCC management aimed at maximizing curative potential and long-term survival.
PMID:41913379 | DOI:10.20892/j.issn.2095-3941.2026.0045
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cs.AI, q-bio.NC updates on arXiv.org
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WebDevJudge: Evaluating (M)LLMs as Critiques for Web Development Quality
arXiv:2510.18560v3 Announce Type: replace-cross Abstract: The paradigm of LLM-as-a-judge is emerging as a scalable and efficient alternative to human evaluation, demonstrating strong performance on well-defined tasks. However, its reliability in open-ended tasks with dynamic environments and complex interactions remains unexplored. To bridge the gap, we introduce WebDevJudge, a systematic benchmark for assessing LLM-as-a-judge performance in web development, with support for both non-interactiv