Normal view
-
cs.AI, q-bio.NC updates on arXiv.org
-
When Does AI Augment Work? A Workflow-Level Framework for Human-Agent Collaboration
arXiv:2609.12482v1 Announce Type: new Abstract: We aim to characterise the value of artificial intelligence in the workplace. Current studies largely measure this value in terms of the current automation capabilities and public adoption of AI. However, such metrics ignore the greater impacts of human--agent collaboration in transforming the nature of work. To account for this, we must expand the scope of our analysis beyond atomised tasks of today, and instead focus on how AI can augment entire
-
cs.AI, q-bio.NC updates on arXiv.org
-
Online Video Agent Harness for Long Video Understanding
arXiv:2609.12818v1 Announce Type: cross Abstract: Long video understanding often behaves like a visual needle-in-a-haystack problem: query-relevant evidence is sparsely distributed across long temporal spans, while packing dense frames into a single VLM context incurs \textit{context rot} and high cost. Existing video agents often rely on query-agnostic offline preprocessing or ad hoc tool sets, which can miss query-specific details and waste computation. In this work, we present VideoXAgent, a
Online Video Agent Harness for Long Video Understanding
-
cs.AI, q-bio.NC updates on arXiv.org
-
Hera: Learning Long-Horizon Coordination for Device-Cloud Collaborative LLM Agents
arXiv:2605.24598v1 Announce Type: new Abstract: Large language model (LLM) agents excel at solving complex long-horizon tasks through autonomous interaction with environments. However, their real-world deployment faces a fundamental device--cloud dilemma: on-device models are efficient but often brittle, while cloud models are stronger but costly in computation. State-of-the-art LLM device--cloud routers usually make coarse task-level decisions, which cannot adapt to the changing difficulty of
Hera: Learning Long-Horizon Coordination for Device-Cloud Collaborative LLM Agents
-
Nature - Issue - nature.com science feeds
-
Electric dipole moment drives the dynamics of the TNFR1 complex I signalosome
Nature, Published online: 01 April 2026; doi:10.1038/s41586-026-10304-1Long-range interactions mediated by protein electric dipole moments have a role in driving the assembly and disassembly of super-signalling complex I for promoting NF-κB signalling.
Electric dipole moment drives the dynamics of the TNFR1 complex I signalosome
Nature, Published online: 01 April 2026; doi:10.1038/s41586-026-10304-1
Long-range interactions mediated by protein electric dipole moments have a role in driving the assembly and disassembly of super-signalling complex I for promoting NF-κB signalling.-
Omics In Lung
-
Trem1 regulates neutrophil metabolism and recruitment in lung ischemia-reperfusion injury
Redox Biol. 2026 Jan 14;92:104026. doi: 10.1016/j.redox.2026.104026. Online ahead of print.ABSTRACTPrimary graft dysfunction (PGD) caused by ischemia-reperfusion injury (IRI) is a major complication after lung transplantation, yet its underlying mechanisms remain unclear. Triggering receptor expressed on myeloid cells 1 (Trem1) is an important mediator of inflammation, but its role in neutrophil function and metabolic reprogramming during lung IRI is not well understood. In this study, we used a
Trem1 regulates neutrophil metabolism and recruitment in lung ischemia-reperfusion injury
Redox Biol. 2026 Jan 14;92:104026. doi: 10.1016/j.redox.2026.104026. Online ahead of print.
ABSTRACT
Primary graft dysfunction (PGD) caused by ischemia-reperfusion injury (IRI) is a major complication after lung transplantation, yet its underlying mechanisms remain unclear. Triggering receptor expressed on myeloid cells 1 (Trem1) is an important mediator of inflammation, but its role in neutrophil function and metabolic reprogramming during lung IRI is not well understood. In this study, we used a murine orthotopic lung transplantation model with cold ischemia and reperfusion, and Trem1 knockout (Trem1-/-) and myeloid-specific Trem1 conditional knockout mice (LysmCreTrem1fl) to explore the role of Trem1 in neutrophil recruitment, neutrophil extracellular trap (NET) formation, and metabolism. Our results show that Trem1 expression increases in both mouse and human lungs after reperfusion and correlates with neutrophil infiltration and lung injury. Trem1 deficiency significantly reduced neutrophil and macrophage recruitment, NET formation, and tissue damage. Multi-omics analysis revealed that Trem1 deletion suppressed oxidative phosphorylation (OXPHOS) and induced a metabolic shift in neutrophils toward glycolysis. In clinical samples, the abundance of TREM1+ neutrophils was correlated with PGD severity and OXPHOS activity. These findings identify Trem1 as a key regulator of neutrophil metabolism and recruitment in lung IRI, and suggest that targeting Trem1 may provide a novel therapeutic strategy to mitigate PGD and improve lung transplant outcomes.
PMID:41861599 | DOI:10.1016/j.redox.2026.104026
-
cs.AI, q-bio.NC updates on arXiv.org
-
Top-Down Semantic Refinement for Image Captioning
arXiv:2510.22391v2 Announce Type: replace-cross Abstract: Large Vision-Language Models (VLMs) face an inherent contradiction in image captioning: their powerful single-step generation capabilities often lead to a myopic decision-making process. This makes it difficult to maintain global narrative coherence while capturing rich details, a limitation that is particularly pronounced in tasks that require multi-step and complex scene description. To overcome this fundamental challenge, we redefine