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Received — 4 April 2026 ⏭

Cell
Restoring circadian rhythms in the hypothalamic paraventricular nucleus reverses aging biomarkers and extends lifespan in male mice Haijiao Zhao · Meimei Liao · Ran Huo · Ting He · Hongni Tian · Zeqi Li · Chen Chen · Ziqing Yu · Juan Chai · Xiaocui Song · Ruichao Shao · Shuhua Ying · Wen Gao · Ling Liu · Di Sang · Qi Li · Haohong Li · Fengchao Wang · Dapeng Ju · Eric Erquan Zhang
Enhancing circadian amplitude in mouse hypothalamic paraventricular nucleus neurons by 3′-deoxyadenosine treatment alleviates age-related pathologies and extends lifespan.
4 March 2026 at 08:00

Restoring circadian rhythms in the hypothalamic paraventricular nucleus reverses aging biomarkers and extends lifespan in male mice

Cell

By: Haijiao Zhao · Meimei Liao · Ran Huo · Ting He · Hongni Tian · Zeqi Li · Chen Chen · Ziqing Yu · Juan Chai · Xiaocui Song · Ruichao Shao · Shuhua Ying · Wen Gao · Ling Liu · Di Sang · Qi Li · Haohong Li · Fengchao Wang · Dapeng Ju · Eric Erquan Zhang

4 March 2026 at 08:00

Enhancing circadian amplitude in mouse hypothalamic paraventricular nucleus neurons by 3′-deoxyadenosine treatment alleviates age-related pathologies and extends lifespan.